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Elizabeth Kwong
kwong Eureka Solutions, Canada

The discovery and development of new drugs is a very complex machine. Despite increasing investments and process improvements in research and development, the survival rates of drugs in late phases of development has languished during the past decade. Recent analysis of such decline in late phase drug development was attributed to non-drug like compounds synthesized by Medicinal Chemists which exhibit low aqueous solubility with highly potent ligands which will bind to a target. With the current challenges facing “big Pharma”, small biotech start-up (BSU’s) with limited internal research and development resources in addition to true virtual pharmaceutical companies (VPC’s) with only an experienced team of managers without any R&D capabilities are quickly emerging which adds another layer of complexity in arriving to a “just right” approach from drug discovery to development. To recover from such failed approaches, a gate-keeper approach is now the norm, where preclinical and discovery collaborations result in a structure and property-based design. This design now used in lead optimization combines biological activity/potency focus with optimizing structural features of the candidate to optimize absorption and pharmacokinetics. This approach is then effectively progressed to the understanding and defining of solid state phase and formulation of the drug candidate when more material is available. Early engagement of the pharmaceutical development scientists on the identification of an optimal phase and formulation during drug discovery can add significant benefits in drug discovery efforts and downstream development. These benefits include the demonstration of dose limiting toxicity to establish acceptable and reproducible safety margins. Another benefit is the early identification of an optimal phase that minimize multiple changes in phase that can contribute to irreproducible plasma levels in various PK studies as candidate are being considered in toxicity studies. Furthermore, formulation development in preclinical studies will also provide some risk mitigation in the development of clinical trial materials. The current presentation will focus on the “must do” list to successfully help progress drug discovery candidates from any pharma organization to development with low risk that provide a balance of speed and quality.

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Delegates are personally responsible for their belongings at the venue. The Organizers will not be held responsible for any stolen or missing items belonging to Delegates, Speakers or Attendees; due to any reason whatsoever.


Registration fees do not include insurance of any kind.


Please note that any (or) all transportation and parking is the responsibility of the registrant.


Press permission must be obtained from Allied Academies Conferences Organizing Committee prior to the event. The press will not quote speakers or delegates unless they have obtained their approval in writing. The Allied Academies is an objective third-party nonprofit organization. This conference is not associated with any commercial meeting company.

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For security purposes, letter of invitation will be sent only to those individuals who had registered for the conference. Once your registration is complete, please contact to request a personalized letter of invitation.

Regarding refunds, all bank charges will be for the registrants account.

This cancellation policy was last updated on December 12, 2016.

Cancellation, Postponement and Transfer of Registration

All cancellations or modifications of registration must be made in writing to

Cancellation Policy

If Allied Academies cancels this event for any reason, you will receive a credit for 100% of the registration fee paid. You may use this credit for another Allied Academies event which must occur within one year from the date of cancellation.


If Allied Academies postpones an event for any reason and you are unable or unwilling to attend on rescheduled dates, you will receive a credit for 100% of the registration fee paid. You may use this credit for another Allied Academies event which must occur within one year from the date of postponement.

Transfer of registration

All fully paid registrations are transferable to other persons from the same organization, if registered person is unable to attend the event. Transfers must be made by the registered person in writing to . Details must be included the full name of replacement person, their title, contact phone number and email address. All other registration details will be assigned to the new person unless otherwise specified.

Registration can be transferred to one conference to another conference of Allied Academies if the person is unable to attend one of conferences.

However, Registration cannot be transferred if it is intimated within 14 days of respective conference.

The transferred registrations will not be eligible for Refund.

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Keeping in view of increased security measures, we would like to request all the participants to apply for Visa as soon as possible.

Allied Academies will not directly contact embassies and consulates on behalf of visa applicants. All delegates or invitees should apply for Business Visa only.

Important note for failed visa applications: Visa issues cannot come under the consideration of cancellation policy of Allied Academies, including the inability to obtain a visa.

Refund Policy:

If the registrant is unable to attend, and is not in a position to transfer his/her participation to another person or event, then the following refund arrangements apply:

Keeping in view of advance payments towards Venue, Printing, Shipping, Hotels and other overheads, we had to keep Refund Policy is as following slabs-

  • Before 60 days of the conference: Eligible for Full Refund less $100 service Fee
  • Within 60-30 days of Conference: Eligible for 50% of payment Refund
  • Within 30 days of Conference: Not eligible for Refund
  • E-Poster Payments will not be refunded.

Accommodation Cancellation Policy:

Accommodation Providers (Hotels) have their own cancellation policies, and they generally apply when cancellations are made less than 30 days prior to arrival. Please contact us as soon as possible, if you wish to cancel or amend your accommodation. Allied Academies will advise the cancellation policy of your accommodation provider, prior to cancelling or amending your booking, to ensure you are fully aware of any non-refundable deposits.


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