Spectroscopy Methods in Drug Discovery
Different spectroscopic procedures are being used in drug discovery studies. There are inventive innovative efforts to put on several mass spectrometric techniques in early drug discovery, preclinical and clinical development, as well as in Phase 0 studies using Accelerator Mass Spectrometry. To examine the small bodies as well as greater molecules, life scientists increasing impart on methods like HPLC, HPTLC, LC-MS. Liquid chromatography-mass spectrometry (LC-MS). It is a systematic technique that couples high resolution chromatographic parting with sensitive and specific mass spectrometric detection and it comprises high performance liquid chromatography (HPLC)-MS. It is perhaps the most powerful technique for pharmaceutical analysis. The applications of LC-MS in pharmaceutical analysis have been in drug metabolism studies, the analysis and identification of impurities and degradation products in pharmaceuticals and the isolation and characterization of potential drug substances from natural synthetic sources.
The International spectrometry business increased from $7.8 bn in 2011 to $8.5 bn through 2011-2012 and it is forecasted to reach $14.8 bn in 2017, at CAGR of 11.7% for the prognosis period of 2012 -2017.