Global assembling of Academicians, Researchers, Scholars & Industry to disseminate and exchange information at 100+ Allied Academics Conferences

Punjab university, India
Title: Nanostructured Lipid Carriers (NLC)-Based gel for the topical delivery of azelaic acid: Designing, characterization and in-vitro evaluation
Biography

Deepinder Singh Malik is an Ph.d student in Punjab University

Abstract

Azelaic acid (AZA) is a naturally occurring dicarboxylic acid, reported to be effective in management of mild to moderate acne vulgaris. However, few noticeable dose-related side effects limit its therapeutic applicability. Therefore, the study was directed towards the optimization, formulation and evaluation of the AZA loaded nano-structured lipid carrier (NLCs) to enhance its payloads and achieve sustained release at the target site. NLCs were prepared by melt emulsification and ultra-sonication method employing glyceryl monostearate and oleic acid as solid and liquid lipid, respectively. The formulation was optimized employing design expert software taking sonication time, amplitude and drug concentration as independent variables with particle size and drug entrapment as dependent variables. The optimized preparation so formed was incorporated into aloe-vera based carbopol gel and evaluated for its size, morphology, pharmacokinetic and pharmacodynamic parameters. NLCs were found to possess mean particle size in a range of 45-48 nm with low polydispersity index value (~ 0.4) and encapsulation efficiency of ca. 82%. It was further verified employing transmission electron microscopy which depicted the formation of uniform surfaced spherical nanoparticles. In-vitro permeation and skin retention studies revealed significant retention of AZA within the skin with minimum penetration across the skin. Draize patch test exhibited no signs of irritation/lesion on the skin indicating its non-irritating nature. Skin distribution analysis employing rhodamine 6G as a fluorescent dye unveiled the deposition of NLCs preparation to the deeper layers of skin. Thus, as per experimental findings, NLCs may be explored as promising carriers for site specific targeting.

Supporting Journals
Special Issues
All accepted abstracts will be published in respective Allied Academies Journals.
Abstracts will be provided with Digital Object Identifier by

Allied Academies Global Conference Directory

Mail us at

For General Queries
drugdiscovery@alliedconferences.org
For Regsirtation Queries
drugdiscovery@alliedmeetings.com
For Exhibitior Queries
drugdiscovery@alliedconferences.org
More details about sponsorship:sponsors@alliedacademies.com

Terms and Conditions

Responsibility

Delegates are personally responsible for their belongings at the venue. The Organizers will not be held responsible for any stolen or missing items belonging to Delegates, Speakers or Attendees; due to any reason whatsoever.

Insurance

Registration fees do not include insurance of any kind.

Transportation

Please note that any (or) all transportation and parking is the responsibility of the registrant.

Press/Media

Press permission must be obtained from Allied Academies Conferences Organizing Committee prior to the event. The press will not quote speakers or delegates unless they have obtained their approval in writing. The Allied Academies is an objective third-party nonprofit organization. This conference is not associated with any commercial meeting company.

Requesting an Invitation Letter

For security purposes, letter of invitation will be sent only to those individuals who had registered for the conference. Once your registration is complete, please contact drugdiscovery@alliedconferences.org to request a personalized letter of invitation.

Regarding refunds, all bank charges will be for the registrants account.

This cancellation policy was last updated on December 12, 2016.

Cancellation, Postponement and Transfer of Registration

All cancellations or modifications of registration must be made in writing to drugdiscovery@alliedconferences.org

Cancellation Policy

If Allied Academies cancels this event for any reason, you will receive a credit for 100% of the registration fee paid. You may use this credit for another Allied Academies event which must occur within one year from the date of cancellation.

Postponement

If Allied Academies postpones an event for any reason and you are unable or unwilling to attend on rescheduled dates, you will receive a credit for 100% of the registration fee paid. You may use this credit for another Allied Academies event which must occur within one year from the date of postponement.

Transfer of registration

All fully paid registrations are transferable to other persons from the same organization, if registered person is unable to attend the event. Transfers must be made by the registered person in writing to drugdiscovery@alliedconferences.org . Details must be included the full name of replacement person, their title, contact phone number and email address. All other registration details will be assigned to the new person unless otherwise specified.

Registration can be transferred to one conference to another conference of Allied Academies if the person is unable to attend one of conferences.

However, Registration cannot be transferred if it is intimated within 14 days of respective conference.

The transferred registrations will not be eligible for Refund.

Visa Information

Keeping in view of increased security measures, we would like to request all the participants to apply for Visa as soon as possible.

Allied Academies will not directly contact embassies and consulates on behalf of visa applicants. All delegates or invitees should apply for Business Visa only.

Important note for failed visa applications: Visa issues cannot come under the consideration of cancellation policy of Allied Academies, including the inability to obtain a visa.

Refund Policy:

If the registrant is unable to attend, and is not in a position to transfer his/her participation to another person or event, then the following refund arrangements apply:

Keeping in view of advance payments towards Venue, Printing, Shipping, Hotels and other overheads, we had to keep Refund Policy is as following slabs-

  • Before 60 days of the conference: Eligible for Full Refund less $100 service Fee
  • Within 60-30 days of Conference: Eligible for 50% of payment Refund
  • Within 30 days of Conference: Not eligible for Refund
  • E-Poster Payments will not be refunded.

Accommodation Cancellation Policy:

Accommodation Providers (Hotels) have their own cancellation policies, and they generally apply when cancellations are made less than 30 days prior to arrival. Please contact us as soon as possible, if you wish to cancel or amend your accommodation. Allied Academies will advise the cancellation policy of your accommodation provider, prior to cancelling or amending your booking, to ensure you are fully aware of any non-refundable deposits.

 

Copyright © 2017-2018 Allied Academies, All Rights Reserved.